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Juvaris has assembled a committed team comprising experienced scientists,
entrepreneurial executives and advisors. The founders of Juvaris
have worked together in the past to produce new and innovative technologies
(including the current technology) and have taken products through
pre-clinical and clinical development towards regulatory approval.
The Juvaris management team and its advisors have a proven track
record in corporate venture financing; building corporate value,
and execution of strategies that realized substantial returns for
investors.
Juvaris Management and Advisory Team:
Grant E. Pickering
Martin D. Cleary
John
F. Warner
Kimberlee Gonzaga
Lee Bussey
Jeff
Fairman
Maggie Sisti
John
S. Morse
Steven
Dow
Grant E. Pickering, President and Chief Executive
Officer
Prior to joining Juvaris, Mr. Pickering founded Pharmada, Inc., where he served as its President and Chief Executive Officer. This biopharmaceutical company focused on the development of small-molecule therapeutics for the treatment of cancer with technology licensed from Fred Hutchinson Cancer Research Center. From 2000 to 2005, Mr. Pickering was employed by Dendreon Corporation in Seattle, Washington and served as a Corporate Officer and most recently as its Senior Vice President of Operations. During his tenure at Dendreon, he led clinical development, manufacturing, sales, marketing, business development, project management and played an important role in fundraising activities, including the company's initial public offering.
Prior to Dendreon, he held senior management roles in marketing and business development with Algos Pharmaceutical Corporation culminating in its sale to Endo Pharmaceuticals for $211M. Mr. Pickering was also employed by Johnson & Johnson's Ortho Pharmaceutical Corporation and Glaxo, Inc., where he was highly successful in positions of increasing responsibility in the area of sales and marketing.
Mr. Pickering earned his B.S. degree in marketing from the Pennsylvania State University in University Park, PA and his MBA degree with honors from Georgetown University in Washington, DC.

Martin D. Cleary, Co-founder, Chairman of the Board of Directors
Mr. Cleary served as the CEO of Juvaris BioTherapeutics from 2003-2008 until he was succeeded by Grant E. Pickering. Mr. Cleary is a prominent health care/biotech industry executive who brings to the company many years of successful and productive experience in both established and early stage companies. He has a history of providing consistent, rapid and extraordinary financial return to investors. His background also includes broad-based general management accomplishments, and a proven track record for building successful organizations. He is widely recognized as a seasoned leader, strong dealmaker and fundraiser in the industry.
Prior to becoming co-Founder and CEO of Juvaris Biotherapeutics Mr. Cleary was President, CEO and a Director at Genteric, Inc. advancing its protein drug delivery technology platforms. Between 1999 and 2002 under his direction, the company raised $32 million in two venture investments and he developed Genteric into a leader in non-viral gene delivery.
Mr. Cleary was co founder, President and CEO of CardioGene Therapeutics, a leading cardiovascular gene therapy company, from its inception in 1996 until its successful merger with Boston Scientific Corporation in 1998. From 1993 to 1994, he was President, CEO and a Director of Theragen, a diversified gene therapy company, which he successfully merged, with GenVec, Inc. of Rockville, Maryland. From 1994 to 1996, he served as a member of the Board of Directors of GenVec, Inc. From 1986 to 1993, he was Group Vice President and Chief Financial Officer of Cytogen Corporation, a biotech company engaged in the development of cancer diagnostics and therapies using monoclonal antibodies.
Prior to joining Cytogen, Mr. Cleary held several senior management positions with Johnson & Johnson over a 14-year career. While serving as Vice President of Operations at J&J's medical device subsidiary Iolab Corporation between 1980 and 1986 the company enjoyed compound growth rates of 40% in sales and 50% in income on revenues in excess of $100 million.
John F. Warner, Ph.D., Co-Founder, Chief Scientific Officer and Vice President, Operations
Dr. Warner is an experienced executive and scientist who brings
to the company over 19 years experience in the biotechnology industry,
much of that in the development of therapeutic vaccines. Dr. Warner
has also been involved the development of therapeutic gene- and
synthetic peptide-based vaccines to induce protective cellular and
humoral immune responses for cancer and infectious diseases as well
as managing immunology and gene therapy research programs.
Dr. Warner most recently completed a three-year association with
Collateral Therapeutics, Inc. as Vice President of Research and
Technology advancing their cardiovascular gene therapy and cardiomics
programs. Prior to Collateral Therapeutics, Dr. Warner held VP-level
positions at Valentis, Inc. and Inex Pharmaceuticals Corporation.
Dr. Warner was previously affiliated with Chiron-Viagene (formerly
Viagene, Inc.) for eight years (1988-1995) where he served in various
supervisory positions including Director, Immunobiology as well
as Head of the HIV immunotherapeutic program. This work resulted
in the initiation of one of the first gene therapy genetic immunization
phase II clinical trials for HIV patients. Dr. Warner was also a
Senior Scientist at the Johnson & Johnson Biotechnology Center
from 1985 to 1988, developing synthetic peptide vaccines. Dr. Warner's
scientific training includes five years as a postdoctoral fellow
at The Salk Institute for Biological Studies and the University
of California, San Diego involved in the study of innate immune
effector systems (cytokines and natural killer cells) and adaptive
immune responses (cellular and humoral). Dr. Warner earned his Ph.D.
in microbiology/immunology from the State University of New York,
Buffalo.
Kimberlee H. Gonzaga, CPA, Chief Financial Officer and Director of Finance
Ms. Gonzaga brings over 13 years of financial management experience, four years of which was spent in public accounting and the last nine in the medical device industry in both established and early stage companies.
Most recently she was with Thoratec Corporation where she held several financial management positions before being named Sr. Strategic Finance Manager. Ms. Gonzaga was responsible for all aspects of consolidated budgeting and planning for multiple divisions, quarterly investor relations for all financial press releases including analyst’s reviews, and worked extensively with business development in all aspects of M&A and other material agreements. Prior to Thoratec Corporation, Ms. Gonzaga held progressive positions with Stryker Corporation, Smith & Nephew, Inc. and with Oratec Interventions, Inc. where she was a key contributor in the Initial Public Offering of the company, the acquisition of a small company and later the acquisition to Smith & Nephew.
Lee Bussey, Senior Vice President of Manufacturing
Dr. Bussey with over 20 years experience, is recognized as a leader in clinical process development and manufacturing, He is a skilled team builder and has lead multiple national/international teams ensuring successful technology transfers and production runs at Contract Manufacturing Organizations (CMOs). His responsibility includes Fermentation, Purification, QC/Analytical, Formulation, Fill/Finish, Facilities and IT.
Previously Dr. Bussey served as Vice President of Bioprocessing for Valentis Inc. While at Valentis Inc.(12+ yrs), his team developed patented technologies for both plasmid DNA purification and formulation, both being critical for Juvaris’ programs. Prior Valentis Inc., Dr. Bussey worked for Pel Freez Biologicals producing nucleic acid, viral and protein based products. He also served in academic positions at the University of Illinois and Georgia State University. Dr. Bussey earned his Ph.D. in Microbiology from the University of California at Davis.
Jeff Fairman, Ph.D., Co-Founder and Vice President, Research
Dr. Fairman is a program manager and experienced scientist in the
use of cationic lipsome-DNA complexes in gene therapy. After receiving
his Ph.D. in Chemistry from the University of Arkansas in 1992,
Dr. Fairman conducted his postdoctoral training at M.D. Anderson
Cancer Center specializing in the genetics of leukemia. While at
M.D. Anderson his research focused on genetic abnormalities in myelodysplastic
syndrome (MDS) and acute myelogenous leukemia (AML). He is an author
of many research publications and review articles in the area of
hematopoetic neoplasms.
In 1996, Dr. Fairman began his industrial experience with AmCell
Corporation working to develop technologies to isolate fetal cells
from maternal blood for cytogenetic analysis. During this time he
was one of three inventors on a patent for PCR additives. In 1997
Dr. Fairman joined Valentis, Inc., where he managed the assay development
group and conducted preclincial efficacy and toxicity studies. He
is also a consultant on quantitative PCR/RT-PCR and in-situ PCR/RT-PCR
at the University of California, Davis, Applied Biosystems and Celera
Diagnostics.
Most recently, Dr. Fairman was the Director of Pharmacogenomics
Research at Clingenix Inc. where he directed research in the application
of pharmacogenomics to clinical development. During his time at
Clingenix, Dr. Fairman was inventor on several patents involving
the application of pharmacogenomics technologies.
Maggie Sisti, Director of Clinical Operations
Ms. Sisti began her career in Research with Genetics Institute and Cypress Bioscience. It eventually led her into Clinical Development as a Clinical Research Associate, Clinical Project Manager, and Clinical Research Manager. Her solid reputation has evolved from extensive experience within contract research organizations, biotechnology, pharmaceutical and vaccine companies (Parexel, Genzyme, Pfizer, Acambis, GSK Biologics). She previously provided clinical operations consultancy for multiple vaccine companies.
John S. Morse, Corporate Secretary
Mr. Morse has over 35 years of experience in engineering, management
and finance in high technology companies. Starting his management
career in technology ventures at Memorex Corporation, he has been
founder, chief financial officer and/or financial consultant to
a number of successful technology startups.
Mr. Morse has an MBA from Santa Clara University and both MS and
BS degrees from Stanford University, where he was a member of Phi
Beta Kappa Honor Society.
Steven Dow, DVM, Ph.D., Co-Founder and Chief Scientific
Advisor
Dr. Dow's current position is as Associate Professor in the Departments
of Clinical Sciences and Pathology in the College of Veterinary
Medicine at Colorado State University. Dr. Dow formerly was an instructor
and research scientist at the National Jewish Medical and Research
Center in Denver.
His current major research interests are in immunotherapeutic approaches
to the treatment of cancer and chronic infectious diseases. Prior
to developing a cancer gene therapy program, his past research has
studied animal models of chronic viral infection (feline immunodeficiency
virus and feline leukemia virus), as well as the role of CD8+ T
cells in immunity to tuberculosis.
Dr. Dow is experienced in the discovery and application of gene
therapy to oncologic and immune-mediated diseases and holds patents
related to cell regulation with gene therapy. He also has several
pending patents, including those that constitute the enabling technology
for Juvaris BioTherapeutics, Inc.
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